DEVELOPING FASTER, SMARTER T CELL FUNCTIONAL ANALYTICS, PERFORMED IN DAYS
Berkeley Lights technology can help speed cell therapy discovery and development by accelerating T Cell Functional Analysis.
T CELL FUNCTIONAL ANALYTICS
WITH A LIMITED NUMBER OF CELLS AND A BEACON PLATFORM, T CELL FUNCTIONAL ANALYSIS REQUIRES JUST 1 DAY.
Cell and gene therapy researchers and manufacturers can benefit greatly from a fast, accurate way to perform T Cell Functional Analytics with a limited number of cells. The Beacon® platform is the answer. We are developing a full range of assays that will automatically generate comprehensive reports, including Surface (%CAR+), Functional Tumor Killing, and Cytokine Secretion assays.
SOME TYPICAL T CELL ASSAYS
Traditional workflows require technicians to process many millions of cells, requiring weeks of work on multiple instruments. But the Beacon platform can gather CAR-T cell functional analytics on thousands of cells in just one day, on a single instrument, completely autonomously.
Because our technology can analyze small quantiles of product cells, sampling happens much earlier in the process. Improve your cellular products by using our OptoSelect™ chips to gather phenotypic and genomic information about the cells displaying the desired cell-killing and cytokine secretion phenotypes.
TUMOR CELL KILLING ASSAY
Multiplex Tumor Killing and IFNɣ Cytokine Assay.
Single Human T Cells (unlabled) are loaded in each nanopen as well as an IFNɣ cytokine secretion ELISA bead. Multiple Tumor cells (magenta) are also loaded. Caspase 3 activation is observed (Cyan) as well as final IFNɣ cytokine secretion levels (yellow).