DEVELOPING FASTER, SMARTER T CELL FUNCTIONAL ANALYTICS, PERFORMED IN DAYS

Berkeley Lights technology can help speed cell therapy discovery and development by accelerating T Cell Functional Analysis.

T Cell

 

T CELL FUNCTIONAL ANALYTICS

WITH A LIMITED NUMBER OF CELLS AND A BEACON PLATFORM, T CELL FUNCTIONAL ANALYSIS REQUIRES JUST 1 DAY.

Cell and gene therapy researchers and manufacturers can benefit greatly from a fast, accurate way to perform T Cell Functional Analytics with a limited number of cells. The Beacon® platform is the answer. We are developing a full range of assays that will automatically generate comprehensive reports, including Surface (%CAR+), Functional Tumor Killing, and Cytokine Secretion assays.

SOME TYPICAL T CELL ASSAYS

Traditional workflows require technicians to process many millions of cells, requiring weeks of work on multiple instruments. But the Beacon platform can gather CAR-T cell functional analytics on thousands of cells in just one day, on a single instrument, completely autonomously.

Because our technology can analyze small quantiles of product cells, sampling happens much earlier in the process. Improve your cellular products by using our OptoSelect™ chips to gather phenotypic and genomic information about the cells displaying the desired cell-killing and cytokine secretion phenotypes.

antigen
CYTOKINE ASSAY

antigen
TUMOR CELL KILLING ASSAY

HOW APPLICATIONS AND TECHNOLOGY COMBINE
ON THE BEACON PLATFORM

 

Beacon Icon

 

VIEW BEACON

Data Output

Multiplex Tumor Killing and IFNɣ Cytokine Assay.

Single Human T Cells (unlabled) are loaded in each nanopen as well as an IFNɣ cytokine secretion ELISA bead. Multiple Tumor cells (magenta) are also loaded. Caspase 3 activation is observed (Cyan) as well as final IFNɣ cytokine secretion levels (yellow).