T CELL FUNCTIONAL ANALYTICS: FUNCTION YOU CAN SEE
VISUALIZE DIVERSE CELL INTERACTIONS.
MEASURE INDIVIDUAL CELL CYTOTOXICITY.
RECOVER CELLS OF INTEREST, ALIVE.
IN YOUR RACE TO DISCOVERY,
HOW CAN YOU FIND THE T CELL FUNCTION YOU DESIRE?
Identifying T cell functional signatures requires long and laborious processes that average individual cell behaviors and interactions. The Lightning™ optofluidic platform changes this by letting you directly visualize the phenotype and function of 100s to 1000s of individual T cells on a single platform in just days.
SEE HOW THE T CELL PHENOTYPE AND CYTOKINE ASSAY
WORKS IN THIS VIDEO.
PRECISELY ASSEMBLE INDIVIDUAL CELL-CELL INTERACTIONS TO VISUALIZE FUNCTION.
The interaction of cells is a critical step in diverse immune cell functions. The Lightning platform lets you precisely build hundreds of cell-cell interactions to perform highly controlled experiments that isolate and investigate individual cell function. This can be applied across many types of experiments including CAR-T construct screening and validation, antigen or TCR discovery and validation, as well as investigation of regulatory T cell function.
QUANTIFY INDIVIDUAL T CELL PROTEIN EXPRESSION AND CYTOKINE SECRETION.
Directly measuring T cell cytotoxicity is challenging. The Lightning platform enables you to directly measure the activation phenotype (CD137) and the function (IFNɣ secretion) of your T cells of interest. This lets you quickly define individual cell variability in your T cell populations and simplifies the process of characterizing cell cytotoxicity. Direct tumor killing assays and multiplex cytokine assays (coming soon) will expand your ability to quickly define T cell function at an individual cell level.
EXPORT YOUR FAVORITE CELLS, ALIVE.
You’ve spent time, energy and resources profiling your T cell population. Wouldn’t you like to recover the most interesting individual cells for further characterization? With the Lightning platform, now you can. Evaluate and visualize your cells and data in our Assay Analyzer software and recover the best cells that meet your export criteria.