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Multi-omic profiling of T cells

To develop effective T cell therapeutics, you need to understand the underlying mechanisms behind powerful phenotypes. It’s now possible to do this with the most potent anti-tumor effector T cells — polyfunctional T cells. Using the OptoSeqSingle Cell 3′ mRNA kit with the Multiplex Cytokine Assay and PrimeSeqsoftware, the OptoCell Therapy Development Workflow lets you: 

  • Identify polyfunctional T cells by measuring the secretion of multiple cytokines 
  • Perform differential gene expression analysis of recovered T cels to gain insight into their transcriptomes 
  • Explore the genetic drivers and pathways behind the most promising T cells 

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This story originally appeared in the Spring/Summer 2021 edition of BLI News. To read more, check out the latest edition.