Go from target to lead molecules in weeks not months with the Opto™ Plasma B Discovery 4.0 workflow.
Use this workflow to:
Screen different species and B cell compartments to recover greater antibody sequence diversity.
In a head-to-head comparison, the Opto Plasma B Discovery workflow delivered lead panels that sample >50-fold greater sequence diversity and spanned a wide range of V gene families including all families from which antibodies were discovered via the hybridoma workflow.
Get the full story in our application note.
Increase the probability of success against difficult and high-value targets by directly screening B cells with assays to identify functional lead molecules.
Direct functional profiling of B cells can yield up to 10-fold more hits than hybridoma campaigns against difficult membrane targets like GPCRs.