Cell Therapy Development
App Note: Perform Multi-omic Analysis to Directly Link T Cell Polyfunctionality to Gene Expression
Download this application note to learn about designing effective therapeutics by directly linking phenotype to gene expression using the OptoSeq™ Single Cell 3ʹ mRNA kit in the Opto™ Cell Therapy Development workflow.
Datasheet: The Opto™ Antigen Presenting Bead Kit
Learn more about the Opto™ Antigen Presenting Bead (Opto™ APB) Kit, its key applications, and how it benefits your cell therapy development workflows by efficiently expanding more antigen-specific T cells than dendritic cells.
Application Note: Unravel the Complexity of Single Natural Killer Cell Cytotoxicity and ADCC Mediation
Explore how the Cytotoxicity Assay can be used to characterize and better understand NK cells in the pursuit of more efficacious cell therapies.
Brochure: Cell Therapy Development
From expanding rare, antigen-specific T cells to fully characterizing them, learn how our capabilities are making cell therapy development more efficient.
Poster: Antigen Validation using Berkeley Lights Opto™ Antigen Presenting Bead Kit
Explore the data from the Opto Antigen Presenting Bead Kit and its ability to relieve a critical bottleneck in the tumor antigen discovery process.
Application Note: Multidimensional Analysis of T Cell Cytotoxicity and Serial Killing Using the Opto™ Cell Therapy Development Workflow
Learn how to use multiple assays on single T cells to finally understand critical functions, such as serial killing, and how they relate to each other.
Application Note: Identify and Select Optimal CAR T Cell Phenotypes with the Opto™ Cell Therapy Development Workflow
Learn how to combine the T Cell Proliferation Assay with either the Multiplex Cytokine Assay or Cytotoxicity Assay to find your most persistent T cells.
Webinar: Expand and Rapidly Validate Antigen-Specific Function of T Cells Using Fewer Cells
Yelena Bronevetsky, PhD, lays out the current challenges in tumor antigen discovery and how our Opto™ Antigen Presenting Bead Kit helps scientists overcome them.
Product Tour: The Opto™ Cell Therapy Development Workflow
Guided by T cell expert, Yelena Bronevetsky, PhD, get a deeper look at how the Opto™ Cell Therapy Development workflow can be used to validate, expand, and fully characterize over a 1,000 T cells.
Brochure: Lightning System
Find out how the Lightning platform lets you visualize diverse cell interactions, measure individual cell cytotoxicity, and recover cells of interest alive.
Webinar: How Pediatric Immune Systems Empower Cancer Immunotherapy
Dr. David Barrett shares insights into why children’s T cells help CAR-T cells succeed and discusses how the Opto Cell Therapy Development Workflow can provide the detailed characterization required to develop more efficacious therapies.
Application Note: Profile and Recover Polyfunctional T Cells Using Multiplexed Cytokine Secretion Assays
Learn how you can easily profile multiple secreted cytokines from live T cells and multiplex with other functional assays.
Datasheet: Cytotoxicity Assay
Learn how to track the kinetics of T cell-tumor cell killing behavior in real time.
Datasheet: Single Cell Cytokine Assays
Review assay overview and results for measuring the release of up to three cytokines from T cells.
Datasheet: TCRseq Well Plate Kit
Review assay overview and results for recovering and amplifying T cell receptor alpha and beta chains.
Application Note: Directly Link T Cell Phenotype and Function to Genotype with the Opto Cell Therapy Development 1.0 Workflow
Review use cases for CAR-T cell screening and TCR discovery.
Poster: T Cell Functional Analytics on the Lightning Platform
See how you can rapidly visualize and analyze thousands of cell-cell interactions in a single-day workflow with live cell recovery.
Poster: T Cell Functional Analytics
This poster describes in detail how to sequence and clone IDH1 R132H targeted monoclonal T cell receptors from CD4+ T cells, using the Beacon system.