T cell-mediated tumor death relies on complex mechanisms and cell-cell interactions, making the development of T cell-based therapies inherently challenging. Understanding T cell differentiation and function is critical for teasing apart the complexity of the tumor microenvironment, however, T cells are exceedingly heterogeneous in both phenotype and function and have variable responses to stimulation.
Download FileReview use cases for CAR-T cell screening and TCR discovery.
Review assay overview and results for recovering and amplifying T cell receptor alpha and beta chains.
Guided by T cell expert, Yelena Bronevetsky, PhD, get a deeper look at how the Opto™ Cell Therapy Development workflow can be used to validate, expand, and fully characterize over a 1,000 T cells.