POSTER: A Rapid High-Throughput Workflow for TCR Discovery on Solid Tumors with Functional Verification

T cell-mediated tumor death relies on complex mechanisms and cell-cell interactions, making the development of T cell-based therapies inherently challenging. Understanding T cell differentiation and function is critical for teasing apart the complexity of the tumor microenvironment, however, T cells are exceedingly heterogeneous in both phenotype and function and have variable responses to stimulation.

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