Poster: Plasma B Cell Cloning

Berkeley Lights and ChemPartner provide a case study in accelerated discovery of unique Anti-PD-L1 antibodies from spleen versus bone marrow of immunized mice, via single plasma B cell cloning on the Beacon platform.

Application Note: Rapid Selection of Antibodies Against Membrane Targets using Cell-Binding Assays and the Opto™ Plasma B Discovery

Find out how the Opto Plasma B Discovery workflow simplifies and dramatically reduces the time needed to down-select potential lead candidates, even for difficult membrane proteins.

APP NOTE: Identify Top Producing Clones with Favorable Product Quality Attributes

• Identify clones with favorable growth, titer, and product quality attributes prior to scale up
• Go from transfected pools to top clones in under one week for a wide variety of protein therapeutics, including protein-based vaccines,
  enzymes and bispecific molecules
• Cloning efficiencies 5x greater than FACS and 10x greater than limiting dilution, and >99% monoclonality assurance