Opto® B Discovery on the Beacon® optofluidic system enables rapid selection of lead candidates by function-forward screening of B cells in under 1 week. This presentation will introduce Berkeley Lights’ newest antibody discovery workflow, the Opto® Memory B Discovery workflow, and share how customers are using the workflow to screen rabbit memory B cells to rapidly discover rabbit monoclonal antibodies (as presented at Antibody Engineering & Therapeutics 2023).