system
Unravel Complex Biology with Single Cell Precision
Deep profiling in one week, on one platform with the Lightning™ optofluidic system.
- Select and clone single cells in just 1 day
- Characterize function in less than one week
- Recover viable cells for further analysis
Single Cell Cloning and Analysis in a New Light
Gain unrivaled insight into biology. Lightning’s novel optofluidic technology enables the isolation and characterization of 1000’s of single cells on one platform.
LIGHTNING APPLICATIONS
Unlimited Potential for Your Research
Functionally profile cells of interest with a wide range of assays powered by a system built to support a diverse range of biological research applications.
ASSAY DEVELOPMENT
Develop reporter cell lines with single-cell precision
- Isolate 1,000 single cells in less than 1 day
- Grow and assay for reporter gene response
kinetics within 3 days - Select and export viable clones for further
growth and analysis
Identification of rare reporter cell lines with robust and homogeneous response.
Functional Studies
Profile thousands of single T cells
- Activate and expand single T cells
- Monitor cell-cell interactions
- Visualize tumor cell killing in real-time
- Detect cytokine secretion
Learn more about our cell therapy development workflow.
What will you accomplish with a Lightning system? Here’s a little more inspiration:
Real-Time Monitoring of Drug-Induced Apoptosis
Multi-omic Analysis to Directly Link T Cell Polyfunctionality to Gene Expression
LIGHTNING technology
Explore Biology at Single-Cell Resolution
Single cell analysis traditionally requires the use of multiple instruments over the course of months. The Lightning system makes it possible to clone, grow, assay, and recover cells in a matter of days.
After automated cloning, assay and monitor cells individually using brightfield and fluorescence. Create a visual record of every cell in every experiment and understand complex biology at a level that’s not possible with any other method.
Single cell cloning
Phenotypic and functional profiling
Live cell-cell interactions
Genomic and transcriptional profiling
Key Features
- All-in-one benchtop design
- Supports OptoSelect™ 1500 chip
- Automated cell selection and loading
- Controllable media perfusion
- Open platform for application flexibility
- Time-lapse imaging throughout experiment
- Real-time visualization of live cells
- Brightfield and 5-color fluorescence detection in FITC, Texas Red, PE, DAPI, and CY5
Related Resources
View All Lightning System ResourcesBrochure: Lightning System
Find out how the Lightning platform lets you visualize diverse cell interactions, measure individual cell cytotoxicity, and recover cells of interest alive.
App Note: Rapid Single-Cell Cloning and Screening to Identify Superior Reporter Cell Lines Using the Lightning™ Optofluidic System
Read this application note to learn more about how to screen reporter cell lines at the single-cell level in only 3 days.
App Note: Real-Time Monitoring of Chemical and Biological Induction of Apoptosis on Clonal Cells Using the Lightning™ System
Read this application note to learn more about observing apoptosis at the single-cell level across 1,000 clonal cells.
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