The Opto™ Cell Therapy Development workflow accelerates the creation of better therapeutics by performing multiple functional assays across 1,000s of individual T cells in a matter of days. Deeply characterize, profile, and map your T cell populations at the single-cell level to directly link phenotype to gene expression.
To realize its potential, you need to deeply characterize it. The Opto Cell Therapy Development workflow lets you directly link single-cell phenotype and function to gene expression. It only takes one cell to create a powerful therapy. We’ll help you find it.
Cells can be selectively cloned into NanoPen™ chambers based on size, viability, and other cell surface markers.
The Opto Cell Therapy Development workflow allows you to investigate complex cell-cell interactions. Our ever-expanding portfolio of capabilities includes assays to study polyfunctionality, cytotoxicity, and to directly link phenotype to genotype and gene expression.
Load beads with your target peptide to expand T cells present at frequencies as low as 0.001%. Then, validate and characterize function with our multiple assays.
Cytokine assays and cell surface markers can be customized.
Now, you can develop therapeutics to mediate more effective tumor destruction by the few T cells that matter.
The TCRseq Well Plate kit allows you to recover your selected cells from fewer than 10,000 cells, amplify TCR alpha and beta chains, and sequence only the T cells that are potential therapeutics.
The OptoSeq™ 3′ mRNA kit is the first of its kind — a combined multi-omics workflow which makes it possible to perform cytokine secretion analysis and gene expression profiling on the same cell.
From expanding rare, antigen-specific T cells to fully characterizing them, learn how our capabilities are making cell therapy development more efficient.
Learn how you can easily profile multiple secreted cytokines from live T cells and multiplex with other functional assays.
Download this application note to learn about designing effective therapeutics by directly linking phenotype to gene expression using the OptoSeq™ Single Cell 3ʹ mRNA kit in the Opto™ Cell Therapy Development workflow.