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See how our customers are applying the T cell workflow to develop a deeper understanding of T cell biology.
Children’s Hospital of Philadelphia on How Immune Systems Empower Cancer Immunotherapy
The Opto® T Cell Profiling workflow accelerates the creation of better therapeutics by performing multiple functional assays across thousands of individual T cells in a matter of days. Deeply characterize, profile, and map your T cell populations at the single-cell level to directly link phenotype to gene expression.
To realize its potential, you need to deeply characterize it. The Opto T Cell Profiling workflow lets you directly link single-cell phenotype and function to gene expression. It only takes one cell to create a powerful therapy. We’ll help you find it.
Specific cells are targeted based on size, viability and cell surface markers. This gentle sorting process does not require repeated media exchange, which can reduce sorter induced cell stress.
The Opto T Cell Profiling workflow makes it possible to comprehensively profile single T cells and link this phenotypic and functional data to the genotype of those same cells.
Multiplex Cytokine Assay Datasheet (PDF)
Cytotoxicity Assay Datasheet (PDF)
TCRseq Kit Datasheet (PDF)
Cytokine assays and cell surface markers can be customized.
Now, you can develop therapeutics to mediate more effective tumor destruction by the few T cells that matter.
The TCRseq Well Plate kit allows you to recover your selected cells from fewer than 10,000 cells, amplify TCR alpha and beta chains, and sequence only the T cells that are potential therapeutics.
The OptoSeq™ 3′ mRNA kit is the first of its kind — a combined multi-omics workflow which makes it possible to perform cytokine secretion analysis and gene expression profiling on the same cell.
Polyfunctionality and cytotoxicity with recovery of live T cells from an integrated platform.
Learn how you can easily profile multiple secreted cytokines from live T cells and multiplex with other functional assays.
Download this application note to learn about designing effective therapeutics by directly linking phenotype to gene expression using the OptoSeq™ Single Cell 3ʹ mRNA kit in the Opto™ Cell Therapy Development workflow.
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